Solutions for Hearing Loss
and Tinnitus
Jeremy G. Turner PhD
401 Timbercreek Drive, Jacksonville, IL 62650\\
(217) 883-1533
Education/Training
B.A. (1995) Illinois College (Psychology)
M.A. (1997) Northern Illinois University (Psychology -Behavioral Neuroscience)
Thesis Title: “Behavioral and Electrophysiological Effects of Exposure to an Augmented
coustic Environment in DBA/2J and C57Bl/6J Mice” Dr. J.F. Willott advisor
Ph.D. (1999) Northern Illinois University (Psychology -Behavioral Neuroscience)
Dissertation Title: “Response Properties of Neurons in the DBA/2J Mouse Inferior Colliculus
Following Exposure to an Augmented Acoustic Environment” Dr. J.F. Willott advisor
Postdoctoral Associate/Researcher IV (2002) Department of Pharmacology, Southern Illinois University School of Medicine. Dr. Donald M.
Caspary mentor.
Positions
2013 – Present: Co-Founder & CEO/CSO, OtoScience Labs Consulting & Contract Research
July, 2006 – Present: Professor of Psychology, Illinois College (Assis. 2006, Assoc. 2009, Full 2015)
August, 2005 – present: Research Assistant Professor (30% FTE), Department of Surgery/Otolaryngology and cross-appointed to Department of Pharmacology, Southern Illinois University School of Medicine.
July, 2002 – July, 2005: Postdoctoral Associate, then research Assistant Professor, Department of Pharmacology, SIU SOM
August, 1999 – July, 2002
Assistant Professor of Psychology, University of Tennessee at Martin
Peer Reviewed Publications and Articles in Preparation
2015, Sametsky, E.A., Turner, J.G., Larson, D., Ling, L., & Caspary, D.M. “Enhanced GABAA-Mediated Tonic Inhibition in Rat Auditory
Thalamus with Behavioral Evidence of Tinnitus.” Journal of Neuroscience, 35(25): 9369-80.
2014, Kalappa, B.I., Brozoski, T.J., Turner, J.G., & Caspary, D.M. “Single-unit hyperactivity and bursting in the thalamus of awake
rats directly correlates with behavioral evidence of tinnitus.” Journal of Physiology, 592(22), 5065-78.
2013, McGovern-Trone, M.M., & Turner, J.G. “The Use of an iPad as a Classroom Tool.” Modern Psychological Studies, 18(2): 31-46.
2013, Turner, J.G., Parrish, J.L., Zuiderveld, L., Darr, S., Hughes, L.F., Caspary, D.M., Idrezbegovic, E., & Canlon, B. “Acoustic Experience
Alters the Aged Auditory System.” Ear & Hearing, 34(2): 151-9.
2012, Llano, D.A., Turner, J.G., & Caspary, D.M. “Diminished thalamocortical feedforward inhibition in an aging mouse model of
chronic tinnitus.” Journal of Neuroscience, 32(46), 16141-8.
2011, Turner, J., Larsen, D., Hughes, L., & Shore, S. “Time Course of Tinnitus Development Following Noise Exposure in Mice.”
Journal of Neuroscience Research, 90(7), 1480
8.
2011, Middleton, J.W., Kiritani, T., Pedersen, C., Turner, J., Shepherd, G.M.G., & Tzounoploulos, T. “Decreased GABAergic Inhibition in
the Dorsal Cochlear Nucleus of Mice with Behavioral Evidence of Tinnitus.” Proceeds of the National Academy of Science (PNAS) USA, 108(18), 7601-6.
2010, Ding, M., Arnold, J., Turner, J.G., Ramkumar, V., Hughes, L.F, Trammell, R.A., & Toth, L.A. “Lack of Association of a
Spontaneous Mutation of the Chrm2 Gene with Behavioral and Physiologic Phenotypic Differences in Inbred Mice. Comparative Medicine, 60(4), 1-10.
2010, Turner, J.G., Hughes, L.F., & Toth, L.A. “Sleep, Activity, Temperature and Arousal Responses of Mice Deficient for Muscarinic
Receptor M2 or M4. Life Sciences, 86, 158-169.
2010, Hughes, L.F., Turner, J.G., Parrish, J.L., & Caspary, D.M. “Processing of broadband stimuli across AI layers in young and aged
rats.” Hearing Research, 264, 79-85.
2009, Wang, H., Brozoski, T.J., Turner, J.G., Ling, L., Parrish, J.L., Hughes, L.F., & Caspary, D.M. “Plasticity at glycinergic synapses in
dorsal cochlear nucleus of rats with behavioral evidence of tinnitus.” Neuroscience, 164, 747-59.
2009, Wang, H., Turner, J.G., Ling, L., Parrish, J., Hughes, L., & Caspary, D. “Age-Related Changes in Glycine Receptor Subunit
Composition and Binding in Dorsal Cochlear Nucleus.” Neuroscience, 160(1), 227-39..
2008, Mukherjea, D., Jajoo, S., Whitworth, C., Bunch, J., Turner, J.G., Rybak, L., & Ramkumar, V. “Short Interfering RNA (siRNA)
Against Transient Receptor Potential Vanniloid-1 (TRPV1) Channel Attenuates Cisplatin-Induced Hearing loss in the Rat. Journal of Neuroscience, 28(49), 13056-65.
2008, Turner, J.G., & Parrish, J. “Gap Detection Methods for Assessing Salicylate-Induced Tinnitus and Hyperacusis in Rats.”
American Journal of Audiology, 17(2), S185-92.
2008, Bauer, C.A., Turner, J.G., Caspary, D.M., Myers, K.S., & Brozoski, T.J. “Tinnitus and Inferior Colliculus Activity in Chinchillas
Related to Three Distinct Patterns of Cochlear Trauma.” Journal of Neuroscience Research, 86, 2564-78.
2008, Caspary, D.M., Ling, L., Turner, J.G., & Hughes, L.F. “Inhibitory Neurotransmission, Plasticity and Aging in the Mammalian
Central Auditory System.” Journal of Experimental Biology, 211, 1781-91.
2007, Turner, J.G. “Behavioral Measures of Tinnitus in Laboratory Animals.” Progress in Brain Research, 166, 147-56.
2007, Turner, J.G., Bauer, C.A., & Rybak, L.P. "Noise in Animal Facilities: Why it Matters." Journal of the American Association of
Laboratory Animal Science, 46, 10-13.
2007 (editorial), Kennedy, B.W., Compton, S., Turner, J.G., & Toth, L.A. "Can You Hear Me Now?" Journal of the American Association
of Laboratory Animal Science, 46, 9.
2006, Yang, G., Lobarinas, E., Zhang, L., Turner, J.G., Stolzberg, D., Salvi, R., Sun, W. “Salicylate Induced Tinnitus: Behavioral
Measures and Neural Activity in the Auditory Cortex of Awake Rats.” Hearing Research, 226, 244-53.
2006, Caspary, D.M., Hughes, L.F., Schatteman, T.A., & Turner, J.G. “Age-related Changes in the Response Properties of Cartwheel
Cells in Rat Dorsal Cochlear Nucleus.” Hearing Research, 216, 207-215.
2006, Turner, J.G., Brozoski, T.J., Bauer, C.A., Parrish, J.L., Myers, K., Hughes, L.F., & Caspary, D.M. “Gap Detection Deficits in Rats
with Tinnitus: A potential Novel Screening Tool.” Behavioral Neuroscience, 120, 188-95.
2005, Turner, J.G., Hughes, L.F., & Caspary, D.M. “Age-related Changes in Response Characteristics of Layer V Neurons in Rat
Primary Auditory Cortex.” Journal of Neurophysiology, 94, 2738-47.
2005, Turner, J.G., Hughes, L.F., & Caspary, D.M. “Divergent Response Properties of Layer V Neurons in Rat Primary Auditory Cortex.”
Hearing Research, 202, 129-140.
2005, Turner, J.G., Parrish, J., Hughes, L.F., Toth, L.A., & Caspary, D.M. "Hearing in Laboratory Animals: Strain Differences and Non-
Auditory Affects of Noise." Comparative Medicine, 55, 12-23.
2005, Turner, J.G. & Caspary, D.M. “Comparison of Two Rat Models of Aging: Peripheral Pathology and GABA Changes in the Inferior
Colliculus.” In Plasticity and Signal Representation in the Auditory System (J. Syka & M.M. Merzenich, Eds.) pp:217-225. Springer: New York, NY.
2004, Hughes, L.F., Turner, J.G., Helfert, R.H. , & Caspary, D.M. "Central Auditory Plasticity in Response to Aging." Experimental
Gerontology, 39, 1772-1773.
2000, Willott, J.F., & Turner, J.G. "Neural Plasticity in the Mouse Inferior Colliculus: Relationship to Hearing Loss, Augmented
Acoustic Stimulation, and Prepulse Inhibition." Hearing Research, 147, 275-281.
2000, Willott, J.F., Turner, J.G., & Sundin, V.S. "Effects of Exposure to an Augmented Acoustic Environment on Auditory Function in
Mice: Roles of Hearing Loss and Age During Treatment." Hearing Research, 142, 79-88.
2000, Falls, W.A., Kogan, J.H., Silva, A.J., Willott, J.F., Carlson, S., & Turner, J.G. "CREBad-Mutant Mice Show Deficient Fear-
Potentiated Startle but Normal Prepulse Inhibition of Startle." Behavioral Neuroscience, 114, 998-1004.
2000, Parham, K., Bonaiuto, G., Carlson, S., Turner, J.G., D’Angelo, W.R., Bross, L.S., Fox, A., Willott, J.F., & Kim, D.O. "Purkinje Cell
Degeneration And Control Mice: Responses of Single Units in the Dorsal Cochlear Nucleus and the Acoustic Startle Response." Hearing Research, 148, 137-152.
1999, Willott, J.F., & Turner, J.G., "Prolonged Exposure to an Augmented Acoustic Environment Ameliorates Age-Related Auditory
Changes in C57BL/6J and DBA/2J Mice." Hearing Research, 135, 78-88.
1998, Turner, J.G., & Willott, J.F. "Exposure to an Augmented Acoustic Environment Alters Auditory Function in Hearing-Impaired
DBA/2J Mice." Hearing Research, 118, 101-113.
1998, Willott, J.F., Turner, J.G., Carlson, S., Ding, D., Bross, L.S., & Falls, W.M. "The BALB/c Mouse as an Animal Model for Progressive
Sensorineural Hearing Loss." Hearing Research, 115, 162-174.
1997, Falls, W.A., Carlson, S., Turner, J.G., & Willott, J.F. "Fear Potentiated Startle in Two Strains of Inbred Mice." Behavioral
Neuroscience, 111, 855-861.
Book
Spalding, E. and Turner, J.G. (2011) “Grandeur in this View of Life: A Brief Introduction to Evolution.” Linus Publications. ISBN:
1607971720.
*A revised second edition is in final edit stages.
Current Research Funding
·Principal Investigator at OtoScience Labs – Awarded research grant from the U.S. Department of Defense, 2014-2017. Title: “Development of a Device for Objective Assessment of Tinnitus in Humans.” $1,500,000
·Principal Investigator at SIU SOM – Awarded research grant from Tinnitus Research Consortium, 2013-2015. Title: “Validation of the Gap Measure for Tinnitus in Humans.” $300,000
·Co-Investigator at SIU SOM (D. Caspary SIU SOM, PI) – United States Department of Defense Office of Naval Research grant from 2012-2015. Title: “A novel GABAA receptor subtype in auditory thalamus in a rat tinnitus model: A potential novel target for tinnitus treatment.” $942,000
Completed/Past Research Funding
·Principal Investigator at SIU SOM – Awarded research grant from Tinnitus Research Consortium, 2009-2012. Title: “Noise Exposure Stimulus Properties and the Temporal Development of Tinnitus.”
·Principal Investigator at SIU SOM – Awarded research contract from Autifony Pharmacueticals
·Co-Investigator at SIU SOM (D. Caspary SIU SOM, PI) – National Institute on Deafness and Communicative Disorders R01 grant from 2007-2012. Title: “The glycine receptor in a rat tinnitus model.”
·Principal Investigator at Illinois College – Awarded research contract from Gedeon-Richter Pharmacueticals. 2011-2012.
·Principal Investigator at Illinois College – Awarded research contract from Merz Pharmaceuticals, 2008-2009.
·Co-Investigator at SIU SOM (T. Tzounopoulos U of Pittsburgh, PI) – American Tinnitus Association grant from 2008-2009. Title: “Cellular mechanisms of tinnitus.”
·Co-Investigator at SIU SOM – (S. Shore U of Michigan, PI) – Tinnitus Research Initiative from 2007-2009. Title: “Neural mechanisms underlying somatic tinnitus.”
·Principal Investigator at SIU SOM -Awarded National Institutes of Health – National Institute on Deafness and Communicative Disorders R21 grant for 2006-2008. Title: “Development of a Rapid Behavioral Tinnitus Screen for Rats.”
·Principal Investigator at SIU SOM – Awarded SIU Excellence in Academic Medicine grant for 2006. Title: “Development of a Rapid Behavioral Tinnitus Screen for Rats.”
·Principal Investigator at SIU SOM -Awarded National Institutes of Health – National Institute on Aging R03 grant for 2004-2006. Title: “Auditory Plasticity in the Aged Mouse.”
·Principal Investigator at SIU SOM-Awarded Central Research Committee grant for 2003-2004. Title: “Effects of Acoustic Environment on the Aged Primary Auditory Cortex: Electrophysiology and Behavior.”
·Co-Investigator at SIU SOM (L. Hughes, PI) -Awarded SIU SOM Excellence in Academic Medicine grant for 2003-2004. Title: “Layer-Specific Changes with Age in Rat Primary Auditory Cortex using a Silicon Multichannel Probe Electrode.”
Affiliation/Accomplishments/Awards
·Member of the Society for Neuroscience, American Association of Laboratory Animal Science, and Association for Research in Otolaryngology.
-Co-inventor (with Michael Kinder) of a technique for objective measurement of tinnitus in animals and humans (US patents 8,088,077 and 8,888,712)
·"Faculty Ambassador Award" for 2014, Illinois College ·Received Concept Development Award from SIU SOM Office of Technology Transfer to develop a prototype with Michael Kinder to measure tinnitus in humans. 2009-1010. Co-investigators include Jun Qin and Haibo Wang of SIU College of Engineering and Michael Kinder – co-inventor.
·2006 Awarded Associated Colleges of Illinois "Shining Example of College Success"
·"Young Alumnus of the Year" for 2002, Illinois College
·"Featured Scholar" for spring semester, 2002, University of Tennessee at Martin.
·“Summit Award” for 2002, Student Government Association for contributions to student life activities at the University of Tennessee at Martin.
·“Glass Apple Research Award” for 2000-2001, College of Education and Behavioral Sciences, University of Tennessee at Martin ·“Distinguished Thesis Award” for 1998, Northern Illinois University (representative at the Midwestern Association of Graduate Schools Master's Thesis Competition)
Selected Professional Service Activities
2014 -Member of the American Tinnitus Association’s Scientific Advisory Committee (4-yr term)
2014 – Alternate Member of the Southern Illinois University School of Medicine’s Laboratory Animal Care and Use Committee
2009-2012 – Member of the Program Committee for the Association for Research in Otolaryngology
2009 – 2012 – Member of the Task Force for Improving Scientific Quality of the Annual Meeting of the American Association of Laboratory Animal Science.
2009 – Served as Outside Expert Reviewer for the National Research Council’s “Recognition and Alleviation of Pain and Distress in Laboratory Animals.” Published by the National Academies Press.
2007-2013 – Member of the Editorial Review Board for the journals Comparative Medicine and the Journal of the American Association of Laboratory Animal Science.
2006 -Guest Editor of special journal issue on "Noise in the Animal Facility" published by the Journal of the American Association of Laboratory Animal Science.
2006-2009 – Member of the Scientific Advisory Committee for the American Association of Laboratory Animal Science
2004-2008 -Member of the Southern Illinois University School of Medicine's Laboratory Animal Care and Use Committee
2000-2002 -Chairman of the UT-Martin Institutional Animal Care and Use Committee.